St. Katharine, known to many as Mother Drexel, built the shrine in 1893 after founding the Sisters of the Blessed Sacrament to serve Native American and African American poor and oppressed people.
The Philadelphia-born St. Katharine was canonized in 2000, 45 years after her death. -via philly.com
For a bio of the saint and a description of her works, click here.
[Update: March 3 is the feast day of Mother Drexel and here's an excellent post.]